Abstract
Recent evidence suggests that fluoride (F) and arsenic (As) may adversely affect intelligence quotient (IQ) scores. We explore the association between exposure to F and As in drinking water and intelligence in children. Three rural communities in Mexico with contrasting levels of F and As in drinking water were studied: Moctezuma (F 0.8+/-1.4 mg/L; As 5.8+/-1.3 microg/L); Salitral (F 5.3+/-0.9 mg/L; As 169+/-0.9 microg/L) and 5 de Febrero (F 9.4+/-0.9 mg/L; As 194+/-1.3 microg/L). The final study sample consisted of 132 children from 6 to 10 years old. After controlling for confounders, an inverse association was observed between F in urine and Performance, Verbal, and Full IQ scores (beta values = -13, -15.6, -16.9, respectively). Similar results were observed for F in drinking water (beta values = -6.7, -11.2, -10.2, respectively) and As in drinking water (beta values= -4.30, -6.40, -6.15, respectively). The p-values for all cases were < 0.001. A significant association was observed between As in urine and Full IQ scores (beta = -5.72, p = 0.003). These data suggest that children exposed to either F or As have increased risks of reduced IQ scores.
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Arsenic and fluoride exposure in drinking water: children’s IQ and growth in Shanyin County, Shanxi Province, China.
Background: Recently, in a cross-sectional study of 201 children in Araihazar, Bangladesh, exposure to arsenic (As) in drinking water has been shown to lower the scores on tests that measure children’s intellectual function before and after adjustment for sociodemographic features. Objectives: We investigated the effects of As and fluoride exposure on
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The effect of high levels of arsenic and fluoride on the development of children’s intelligence.
In the fields of toxicology, histology, physiology and biochemistry, numerous research and reports have already been conducted on the poisonous effect of arsenic poisoning, fluoride poisoning, as well as the combined effect of arsenic and fluoride poisoning. Progress has been made likewise in relevant medical treatment, clinical diagnosis and water clean-up prevention
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A Systems Approach to Remediating Human Exposure to Arsenic and Fluoride From Overexploited Aquifers.
Key Points Overexploiting aquifers increases energy costs and lowers economic productivity by increasing human exposure to geogenic neurotoxins Over a 100 year future time-frame estimated revenue from agro-export will be less than the costs this activity imposes on the population Investing in water treatment substantially lowers costs of deteriorating water quality In
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Arsenic and fluoride co-exposure through drinking water and their impacts on intelligence and oxidative stress among rural school-aged children of Lahore and Kasur districts, Pakistan.
Arsenic (As), and fluoride (F-) are potent contaminants with established carcinogenic and non-carcinogenic impacts on the exposed populations globally. Despite elevated groundwater As and F- levels being reported from various regions of Pakistan no biomonitoring study has been reported yet to address the co-exposure impact of As and F- among
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Influence of fluoride exposure on reaction time and visuospatial organization in children
Note: This is a conference abstract from the 2000 Annual Conference of the ISEE (International Society for Environmental Epidemiology). No full study has been published. Fluoride exposure is an important public health problem in several Mexican states. In the city of San Luis Potosi, Mexico, above 90% of the children have
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NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects
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